Seguin, Texas, November 22, 2025

A multi-vehicle crash occurred on eastbound Interstate 10 in Seguin, Texas, involving six vehicles and leading to at least two individuals being hospitalized. The accident caused significant traffic delays, prompting authorities to advise motorists to seek alternative routes. The investigation into the cause of the crash is ongoing. This incident follows several recent traffic incidents in the area, raising safety concerns for drivers. Authorities urge caution and adherence to speed limits.

Seguin Traffic Alert: Multi-Vehicle Crash on I-10 Results in Hospitalizations

Seguin, Texas – A multi-vehicle collision occurred on eastbound Interstate 10 near Texas 123 in Seguin on Friday, November 21, 2025, just before 3 p.m., leading to at least two individuals being transported to the hospital.

Crash Details

The Guadalupe County Sheriff’s Office reported that the incident involved six vehicles, including two semitrailers. While specific details about the injuries remain undisclosed, two people were taken to the hospital for treatment. The exact number of lanes affected and the duration of the traffic backup are currently unclear. Authorities are continuing to investigate the cause of the crash.

Traffic Impact

Following the accident, traffic in the area experienced significant delays. Drivers are advised to seek alternative routes and exercise caution when traveling through the region. Updates on road conditions and any potential lane closures will be provided as more information becomes available.

Recent Traffic Incidents in Seguin

This incident follows a series of traffic-related events in the Seguin area. Notably, on October 22, 2025, a fatal crash occurred at the intersection of State Highway 123 Bypass and Interstate 10, resulting in the death of a 63-year-old man and injuries to two others. Additionally, on November 7, 2025, a fiery 18-wheeler crash led to the closure of parts of Interstate 10 and the State Highway 123 Bypass in Seguin. These events highlight ongoing traffic safety concerns in the region.

Safety Recommendations

Authorities urge all motorists to remain vigilant, adhere to posted speed limits, and exercise caution, especially in areas with heavy traffic or ongoing investigations. Staying informed about road conditions and potential hazards can help prevent accidents and ensure the safety of all road users.

Contact Information

For more information on traffic updates and road conditions, please refer to official channels or local news outlets. Motorists are encouraged to stay informed and plan their routes accordingly to avoid delays and ensure a safe journey.

Frequently Asked Questions (FAQ)

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Key Features of the Incident

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